The Expora Platform™

The Expora Platform™ unlocks an innovative new type of extracellular vesicle (EV) immunotherapy

Platform

A Breakthrough in Extracellular Vesicles

The Expora Platform™ overcomes critical manufacturing barriers to unlock the potential of EVs to deliver gut-targeted, multi-specific immunotherapy for initial applications in management of complex immune-mediated GI diseases. By reducing costs 100-fold, we pave the way for promising new applications of EVs.

Platform

A Breakthrough in Extracellular Vesicles

The Expora Platform™ overcomes critical manufacturing barriers to unlock the potential of EVs to deliver gut-targeted, multi-specific immunotherapy for initial applications in management of complex immune-mediated GI diseases. By reducing costs 100-fold, we pave the way for promising new applications of EVs.

Platform

A Breakthrough in Extracellular Vesicles

The Expora Platform™ overcomes critical manufacturing barriers to unlock the potential of EVs to deliver gut-targeted, multi-specific immunotherapy for initial applications in management of complex immune-mediated GI diseases. By reducing costs 100-fold, we pave the way for promising new applications of EVs.

3x

3x

3x

Potency

Potency

Potency

60x

60x

60x

Yield

Yield

Yield

10-100x

10-100x

10-100x

Lower Cost

Lower Cost

Lower Cost

Synthetic Biology Platform

The Expora Platform™ applies the power of synthetic biology by genetically programming non-inflammatory bacteria originally isolated from the human body for production of gut-targeted, multi-specific EV therapeutics. A product of over a decade in development and $10M of federally-funded research, our technology derisks the most critical barriers to EV development

The Expora Platform™ applies the power of synthetic biology by genetically programming non-inflammatory bacteria originally isolated from the human body for production of gut-targeted, multi-specific EV therapeutics. A product of over a decade in development and $10M of federally-funded research, our technology derisks multiple aspects of EV development.

Scalable Manufacturing

The Expora Platform™ unlocks potential for large commercial scale EV manufacturing through homogenous producer cells, selective multimode purification, and stringent quality controls. Our cost-effective processes have potential to scale to produce tens of millions of doses per year, with unmatched consistency.

Precision Medicine by Design

Expora's gut-targeted, multi-specific EVs are the ideal modality to treat immune-mediated GI diseases, where conventional modalities face safety, efficacy, or delivery limitations. Our modular EV design begins with a chassis targeting fundamental immune processes underpinning numerous GI diseases, upon which designer therapeutic cargo (e.g., antibodies) can be loaded without sacrificing manufacturing consistency to target clinically-validated pathways.

Manufacturing Excellence

Manufacturing Excellence

From Lab to Life

From Lab to Life

Our Experts at Expora Therapeutics have designed a rapidly scalable platform to generate an array of extracellular vesicles to target a multitude of patient populations. This platform is capable of engineering EVs with specific cargo, purifying particles from multiple sources, and isolating the most potent EV subtypes to produce the greatest clinical impact.

Our Experts at Expora Therapeutics have designed a rapidly scalable platform to generate an array of extracellular vesicles to target a multitude of patient populations. This platform is capable of engineering EVs with specific cargo, purifying particles from multiple sources, and isolating the most potent EV subtypes to produce the greatest clinical impact.

Partner With Us to Advance the Future of Extracellular Vesicle Therapeutics

We are seeking collaborators, funders, scientific and strategic partners who share our commitment to advancing the future of exosome therapeutics.

Partner With Us to Advance the Future of Extracellular Vesicle Therapeutics

We are seeking collaborators, funders, scientific and strategic partners who share our commitment to advancing the future of exosome therapeutics.

Partner With Us to Advance the Future of Extracellular Vesicle Therapeutics

We are seeking collaborators, funders, scientific and strategic partners who share our commitment to advancing the future of exosome therapeutics.